3-(3-Chloro­benzo­yl)-4-hydr­oxy-2H-1,2-benzothia­zine 1,1-dioxide

نویسندگان

  • Zunera Khalid
  • Hamid Latif Siddiqui
  • Matloob Ahmad
  • Sana Aslam
  • Masood Parvez
چکیده

In the title compound, C(15)H(10)ClNO(4)S, the heterocyclic thia-zine ring adopts a half-chair conformation with the S and N atoms displaced by 0.476 (5) and 0.227 (5) Å, respectively, on opposite sides of the mean plane formed by the remaining ring atoms. The structure is stabilized by inter-molecular N-H⋯O and C-H⋯O hydrogen bonds. In addition, intra-molecular O-H⋯O and C-H⋯N inter-actions are also present.

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In the crystal structure of the title compound, C(18)H(18)N(2)O(4)S, the thia-zine ring adopts a distorted half-chair conformation. 1,2-Benzothia-zines of this kind have a wide range of biological activities and are mainly used as medicines in the treatment of inflammation and rheumatoid arthritis. The enolic H atom is involved in an intra-molecular O-H⋯O hydrogen bond, forming a six-membered r...

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عنوان ژورنال:

دوره 66  شماره 

صفحات  -

تاریخ انتشار 2010